Bispecific CXCR4-CD-4 polypeptides with potent anti-HIV activity

The present invention relates to bispecific polypeptides that are directed against the cellular receptor CD4 as well as a cellular co-receptor for HIV. Said polypeptides may be used to prevent human cell entry of HIV.

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Bibliographische Detailangaben
Hauptverfasser: Stortelers, Catelijne, Vanlandschoot, Peter, Schols, Dominique, Van Rompaey, Philippe, Soares, Hugo
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to bispecific polypeptides that are directed against the cellular receptor CD4 as well as a cellular co-receptor for HIV. Said polypeptides may be used to prevent human cell entry of HIV.