CD37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof

H:\ft\interwoven\NRPortbl\DCC\FMT\l0053907_ .docx-27/04/2016 The present disclosure provides a humanized anti-CD37 small modular immunopharmaceutical (SMIP) molecule, as well as synergistic combination therapies of CD37-specific binding molecules (such as anti-CD37 SMIP proteins or antibodies) with...

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Hauptverfasser:	SIMON, SANDY ALEXANDER, HAYDEN-LEDBETTER, MARTHA SUSAN, THOMPSON, PETER ARMSTRONG, LEDBETTER, JEFFREY A, CERVENY, CHARLES G, BRADY, WILLIAM, NILSSON, CHRISTY ANNE, MORALES, CECILE, TAN, PHILLIP
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Zusammenfassung:	H:\ft\interwoven\NRPortbl\DCC\FMT\l0053907_ .docx-27/04/2016 The present disclosure provides a humanized anti-CD37 small modular immunopharmaceutical (SMIP) molecule, as well as synergistic combination therapies of CD37-specific binding molecules (such as anti-CD37 SMIP proteins or antibodies) with bifunctional chemotherapeutics (such as bendamustine) that can be administered concurrently or sequentially, for use in treating or preventing B cell related autoimmune, inflammatory, or hyperproliferative diseases.