Alternative Synthesis of Liposome and Determination of Critical Micelle Concentration

The present invention comprises of a new liposome possessing a hydrophobic fatty acid tail with a hydrophilic protocatechuic acid head group. The liposome C 4 3 0 6 H 1 0 4 and synthetic procedure is described. That being the use of an alteration of Fischer esterification to bond the protocatechuic acid to two activated oleic acid carbon chains through an ester bond to form a carboxylic acid ester liposome. The further addition of a hyaluronic acid adjuvant to the protocatechuic acid head group through a disulfide spacer is also described. That being liposome C6 0 0 1 6 N 3H 1 3 2 involving only one unit of the hyaluronic acid to determine the chemical formula. Characterisation is determined by finding the critical micelle concentration using UV-vis and by titration with HCl.