Mutant IDH1 inhibitors useful for treating cancer

Mutant IDH1 inhibitors useful for treating cancer

Compounds of Formula I and Formula II and the pharmaceutically acceptable salts thereof are disclosed The variables A, B, Y, Z, X

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Bibliographische Detailangaben
Hauptverfasser: Karavadhi, Surendra, Rohde, Jason Matthew, Pragani, Rajan, Urban, Daniel Jason, McIver, Andrew Louis, Simeonov, Anton, Jadhav, Ajit, Davis, Mindy Irene Emily, Wang, Xiaodong, Liu, Li, Boxer, Matthew Brian, Brimacombe, Kyle Ryan, Shen, Min
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Compounds of Formula I and Formula II and the pharmaceutically acceptable salts thereof are disclosed The variables A, B, Y, Z, X