Alpha-aminoamide derivative compound and pharmaceutical composition containing the same

The present invention relates to an alpha-aminoamide derivative compound and a pharmaceutical composition comprising the same. According to various embodiments of the present invention, provided is a therapeutic agent which can overcome the disadvantages of conventional drugs used as a MAO-B inhibit...

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Bibliographische Detailangaben
Hauptverfasser: Heo, Jun Young, Jo, Seon Mi, Park, Jong-Hyun, Min, Sun Joon, Kim, Yun Kyung, Choo, Hyun Ah, Nam, Min Ho, Song, Hyo Jung, Ju, Eun Ji, Pae, Ae Nim, Kim, Dong Jin, Choi, Ji Won, Yeon, Seul Ki, Kang, Yong Koo, Park, Ki Duk, Jang, Bo Ko, Lee, Changjoon Justin
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to an alpha-aminoamide derivative compound and a pharmaceutical composition comprising the same. According to various embodiments of the present invention, provided is a therapeutic agent which can overcome the disadvantages of conventional drugs used as a MAO-B inhibitor and, more specifically, reversibly inhibits MAO-B through a non-covalent bond so as to alleviate or eliminate the side effects of conventional drugs by irreversibly acting via a covalent bond with MAO-B to exhibit a therapeutic effect. Particularly, a new compound may be provided having superior stability and efficacy compared to a conventional reversible MAO-B inhibitor.