A neural substrate for sugar preference

This invention concerns a composition and a method of modulating the craving and/or desire for natural sugar in a subject comprising: agonizing or stimulating or antagonizing or silencing a selective group of neurons in the cadual nucleus of the solitary tract (cNST) of the brain in the subject, wit...

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Bibliographische Detailangaben
Hauptverfasser: Lessard, Ryan T, Goffer, Yossef, Zuker, Charles
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention concerns a composition and a method of modulating the craving and/or desire for natural sugar in a subject comprising: agonizing or stimulating or antagonizing or silencing a selective group of neurons in the cadual nucleus of the solitary tract (cNST) of the brain in the subject, wither directly or via the gut or gut-brain axis.