P2X7 modulators

The present invention is directed to compounds of Formula (I), which includes enantiomer and diasteromers thereof. The invention also relates to pharmaceutical compositions comprising compounds of Formula (I). Methods of making and using the compounds of Formula (I) as P2X7 modulators are also withi...

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Bibliographische Detailangaben
Hauptverfasser:	Wall, Jessica L, Rech, Jason C, Letavic, Michael A
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention is directed to compounds of Formula (I), which includes enantiomer and diasteromers thereof. The invention also relates to pharmaceutical compositions comprising compounds of Formula (I). Methods of making and using the compounds of Formula (I) as P2X7 modulators are also within the scope of the invention.