Nitrobenzaldehyde proton release for manipulation of cellular acidosis

Certain embodiments are directed to photo-activated compounds for the manipulation of pH in a cell. In certain aspects the photo-activated compound is 2-nitrobenzaldehyde (NBA). Photo-activated compounds can be used as a targeted therapy for a variety of disease states and conditions, such as cancer...

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Hauptverfasser: Gdovin, Matthew, Hazlett, Haley, O'Grady, Brian, Frias, Elma
Format: Patent
Sprache:eng
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Zusammenfassung:Certain embodiments are directed to photo-activated compounds for the manipulation of pH in a cell. In certain aspects the photo-activated compound is 2-nitrobenzaldehyde (NBA). Photo-activated compounds can be used as a targeted therapy for a variety of disease states and conditions, such as cancer.