Microbiological process

A process for the microbial synthesis of migalastat, specifically a process for the production of migalastat comprising culturing a microorganism under conditions such that at least one imino sugar is produced and detecting and/or isolating an imino sugar produced by said microorganism, and the micr...

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Bibliographische Detailangaben
Hauptverfasser: VAZQUEZ MUNIZ, MARIA JESUS, DANN, ALISON SARAH, READY, SARAH JANE, COLLIS, ANDREW JOHN, FOSBERRY, ANDREW PETER, ALVAREZ-RUIZ, EMILIO
Format: Patent
Sprache:eng
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Zusammenfassung:A process for the microbial synthesis of migalastat, specifically a process for the production of migalastat comprising culturing a microorganism under conditions such that at least one imino sugar is produced and detecting and/or isolating an imino sugar produced by said microorganism, and the microorganisms used in this process. The invention also comprises migalastat produced according to the above method and pharmaceutical compositions and uses thereof.