Novel assay to detect human periostin

Novel assay to detect human periostin

This disclosure provides a robust, sensitive, and specific assay for the detection and measurement of periostin levels in samples obtained from human patients having, or suspected of having an IL-13-mediated disease or disorder. The disclosure further provides novel antiperiostin monoclonal antibodi...

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Bibliographische Detailangaben
Hauptverfasser: DILLE, BRUCE, VARKEY, REENA, PARKER, MELISSA, BROPHY, SUSAN, LEE, YEN-WAH, STREICHER, KATIE, YAO, YIHONG, DAVIS, GERARD, GRANT, ETHAN, GREENLEES, LYDIA, CHOWDHURY, PARTHA, RANADE, KOUSTUBH, JEANBLANC, NICOLETTE, LIANG, MEINA
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Beschreibung
Zusammenfassung:This disclosure provides a robust, sensitive, and specific assay for the detection and measurement of periostin levels in samples obtained from human patients having, or suspected of having an IL-13-mediated disease or disorder. The disclosure further provides novel antiperiostin monoclonal antibodies that recognize at least isoforms 1, 2, 3, 4, 7, and 8 of human periostin, and assay kits comprising one or more of these antibodies.