Systems and methods for registration of images

- 40 SYSTEMS AND METHODS FOR REGISTRATION OF IMAGES Systems and methods for registering images are described. One method aligns a fixed image with a corresponding moving image. A target image and a reference image are selected 5 (304). The target image is a relatively low resolution representation of the moving image and the reference image is a relatively low resolution representation of the fixed image. A current image distortion map is determined that defines distortions between the selected target image and reference image (306). A residual image is determined by comparing the reference image and a warped target image derived from the target image based on the current image .0 distortion map (520). Further, a residual image distortion map is determined based on transform coefficients of cosine functions fitted to the residual image (530). The transform coefficients are determined by applying a discrete cosine transform to a signal formed by the residual image and image gradients of the warped target image or the reference image . The current image distortion map is combined with the residual image distortion map to align the .5 fixed image and the moving image (203). /1 - 1 -O'l 1\. AVT C, 200 Start Select a fixed image and a moving image Calculate an image distortion map mapping fixed image to moving image 203 Warp the moving image onto the fixed using the distortion map View fixed and warped moving image CStopD Fig. 2 10098432 P1 39583_Figs