Antibodies against a proliferating inducing ligand (APRIL)

The present invention relates to a binding compound which binds to human APRIL. More specifically the invention provides, compositions of anti-APRIL specific antibodies and methods to use such antibodies in modulating the biological activity APRIL, particularly in inflammatory diseases, inhibition o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KIMBERLEY, FIONA CLARE, PHAN, UYEN TRUONG, GUADAGNOLI, MARCO, MEDEMA, JAN PAUL, VAN EENENNAAM, HANS
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a binding compound which binds to human APRIL. More specifically the invention provides, compositions of anti-APRIL specific antibodies and methods to use such antibodies in modulating the biological activity APRIL, particularly in inflammatory diseases, inhibition of cell proliferation and cancer.