Estrogen receptor beta agonists for use in treating mesothelioma

The invention provides a treatment of mesothelioma, especially malignant pleural mesothelioma, using an estrogen receptor subtype (ER ) agonist, wherein the treatment comprises administering the ER agonist to the patient, and then after a time, t, of up to 24 hours; administering a platinum-containi...

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Bibliographische Detailangaben
Hauptverfasser: NILSSON, STEFAN, PINTON, GIULIA, MANENTE, ARCANGELA GABRIELLA, MORO, LAURA
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides a treatment of mesothelioma, especially malignant pleural mesothelioma, using an estrogen receptor subtype (ER ) agonist, wherein the treatment comprises administering the ER agonist to the patient, and then after a time, t, of up to 24 hours; administering a platinum-containing anti-cancer drug to the patient. The invention also provides an ER agonist and a platinum-containing anti-cancer drug for use in the treatment of mesothelioma in a patient, wherein the treatment comprises administering the ER agonist to the patient, and then after a time, t, of up to 24 hours, administering the platinum- containing anti-cancer drug to the patient; and a kit comprising a platinum-containing anti- cancer drug and an ER agonist.