Fatty acid derivatives of dimeric inhibitors of PSD-95

Fatty acid derivatives of dimeric inhibitors of PSD-95

The present invention provides fatty acid derived compounds capable of binding to the PDZ domains of PSD-95 and their medical use as inhibitors of protein-protein interaction mediated by PSD-95.

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Bibliographische Detailangaben
Hauptverfasser: Bach, Anders, Stromgaard, Kristian, Nissen, Klaus Bertram
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention provides fatty acid derived compounds capable of binding to the PDZ domains of PSD-95 and their medical use as inhibitors of protein-protein interaction mediated by PSD-95.