Compositions comprising heterogeneous populations of recombinant human clotting factor Xa proteins

Compositions are provided comprising recombinant variants of the human clotting Factor Xa. Such compositions include a wide variety of isoforms and post-translational modifications of FXa and are useful for treating subjects in need of hemostasis.

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Bibliographische Detailangaben
Hauptverfasser: ROUSE, JASON C, SWITZER, MARY BETH, JOHNSON, KEITH A, WESTON, STACEY B, SHARPE, PENELOPE JANE, JANKOWSKI, MICHAEL ANTHONY, SHAMASHKIN, MICHAEL, PIACENZA, WENDY CAROL
Format: Patent
Sprache:eng
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Zusammenfassung:Compositions are provided comprising recombinant variants of the human clotting Factor Xa. Such compositions include a wide variety of isoforms and post-translational modifications of FXa and are useful for treating subjects in need of hemostasis.