Heterobicycloaryl RORC2 inhibitors and methods of use thereof

The present invention provides compounds, pharmaceutical compositions, methods of inhibiting RORy activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such compounds and pharmaceutical compositions.

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Bibliographische Detailangaben
Hauptverfasser:	Xing, Li, Kiefer Jr., James Richard, Schnute, Mark Edward, Wennerstal, Goran Mattias, Flick, Andrew Christopher, Zapf, Christoph Wolfgang, Blinn, James Robert, Thorarensen, Atli, Kaila, Neelu, Meyers, Marvin Jay, Zamaratski, Edouard, Mente, Scot Richard, Kurumbail, Ravi G, Jones, Peter
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides compounds, pharmaceutical compositions, methods of inhibiting RORy activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such compounds and pharmaceutical compositions.