Platform for targeted delivery to stem cells and tumor cells and uses thereof

The invention involves therapy and diagnostics using nanoparticles that provide targeted delivery of agents to cancer cells and stem cells,including cancer stem cells, the nanoparticles being pH sensitive and incorporating cytotoxic ceramides.

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Bibliographische Detailangaben
Hauptverfasser: CARVALHO DA FONSECA, NUNO ANDRE, DANTAS NUNES CALDEIRA DE MOURA, VERA LUCIA, SERENO DE ALMEIDA MOREIRA, JOAO NUNO, GOMES DA SILVA, LIGIA CATARINA, DE MAGALHAES SIMOES, SERGIO PAULO
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention involves therapy and diagnostics using nanoparticles that provide targeted delivery of agents to cancer cells and stem cells,including cancer stem cells, the nanoparticles being pH sensitive and incorporating cytotoxic ceramides.