Methods for localized modification of tissue products

Methods for treating tissue matrices and tissue matrices produced according to the methods are provided. The methods can include treating select portions of a tissue matrix with a cross-linking agent and/or a proteolytic enzyme to produce a tissue matrix with variable mechanical and/or biological pr...

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Hauptverfasser: RODRIGUEZ, NEIL L, MONTEIRO, GARY, DELOSSANTOS, AUBREY IRENE, WAGNER, CHRISTOPHER T
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Methods for treating tissue matrices and tissue matrices produced according to the methods are provided. The methods can include treating select portions of a tissue matrix with a cross-linking agent and/or a proteolytic enzyme to produce a tissue matrix with variable mechanical and/or biological properties.