Spiro-quinazolinone derivatives useful for the treatment of neurological diseases and conditions

Spiro-quinazolinone derivatives useful for the treatment of neurological diseases and conditions

The present invention relates to novel spiro-quinazolinone derivatives as positive allosteric modulators for modulating metabotropic glutamate receptor subtype 4 (mGluR4) and/or altering glutamate level or glutamatergic signalling

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Bibliographische Detailangaben
Hauptverfasser: Hodous, Brian L, Johnson, Theresa L, Haxell, Thomas Francis Nelson, Dorsey, James M, Foglesong, Robert James, Brugger, Nadia, Potnick, Justin, Sutton, Amanda E, Richardson, Thomas E
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention relates to novel spiro-quinazolinone derivatives as positive allosteric modulators for modulating metabotropic glutamate receptor subtype 4 (mGluR4) and/or altering glutamate level or glutamatergic signalling