Treatment method using EGFR antibodies and src inhibitors and related formulations

TREATMENT METHOD USING EGFR ANTIBODIES AND SRC INHIBITORS AND RELATED FORMULATIONS The present invention relates to the treatment of EGFR-mediated disease, particularly cancer by inhibiting or blocking EGFR and src in combination or simultaneously. The invention relates to treatment, prevention, or...

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Bibliographische Detailangaben
Hauptverfasser: FURNARI, FRANK, JOHNS, TERRANCE GRANT, CAVENEE, WEBSTER, SCOTT, ANDREW
Format: Patent
Sprache:eng
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Zusammenfassung:TREATMENT METHOD USING EGFR ANTIBODIES AND SRC INHIBITORS AND RELATED FORMULATIONS The present invention relates to the treatment of EGFR-mediated disease, particularly cancer by inhibiting or blocking EGFR and src in combination or simultaneously. The invention relates to treatment, prevention, or modulation of cancer, particularly EGFR- mediated disease, with one or more EGFR modulator and src inhibitor in combination. The invention further relates to the treatment of cancer with anti-EGFR antibodies and src inhibitors. Methods and compositions for treatment of cancer with the antibody anti- EGFR mAb806 in combination or series with a src inhibitor or src inhibitors are described.