Sulfonyl amide derivatives for the treatment of abnormal cell growth

Abstract The present invention relates to a compound of the formula I R4 -N HN-(CR2 R3), B 5 (R)m wherein R' to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also rel...

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Bibliographische Detailangaben
Hauptverfasser:	XIAO, JUN, LUZZIO, MICHAEL JOSEPH, FREEMAN-COOK, KEVIN DANIEL, AUTRY, CHRISTOPHER LOWELL, HULFORD, CATHERINE ANGELA, BHATTACHARYA, SAMIT KUMAR, HAYWARD, MATTHEW MERRILL, ZHAO, XUMIAO, NELSON, KENDRA LOUISE
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Abstract The present invention relates to a compound of the formula I R4 -N HN-(CR2 R3), B 5 (R)m wherein R' to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the 0 treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.