Purine inhibitors of human phosphatidylinositol 3-kinase delta

The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflamation, asthma, COPD and cancer.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Leng, Xiansheng, Methot, Joey L, Anthony, Neville John, Zhou, Hua, Achab, Abdelghani Abe, Altman, Michael D, Ye, Baijun, Zhao, Xiaoli, Christopher, Matthew P, Fradera Llinas, Francesc Xavier, Mu, Changwei, Yang, Liping, Zhang, Sixing, Deng, Yongqi, Katz, Jason D, Garcia, Yudith, Wang, Xiaona, Zhang, Rong, McGowan, Meredeth, Shi, Feng, Kattar, Solomon, Fong, Kin Chiu
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Leng, Xiansheng
Methot, Joey L
Anthony, Neville John
Zhou, Hua
Achab, Abdelghani Abe
Altman, Michael D
Ye, Baijun
Zhao, Xiaoli
Christopher, Matthew P
Fradera Llinas, Francesc Xavier
Mu, Changwei
Yang, Liping
Zhang, Sixing
Deng, Yongqi
Katz, Jason D
Garcia, Yudith
Wang, Xiaona
Zhang, Rong
McGowan, Meredeth
Shi, Feng
Kattar, Solomon
Fong, Kin Chiu
description The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflamation, asthma, COPD and cancer.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_AU2013347539BB2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>AU2013347539BB2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_AU2013347539BB23</originalsourceid><addsrcrecordid>eNrjZLALKC3KzEtVyMzLyEzKLMkvKlbIT1PIKM1NzFMoyMgvLshILMlMqczJzMsvBkrnKBjrZmfmJRanKqSk5pQk8jCwpiXmFKfyQmluBhU31xBnD93Ugvz41OKCxOTUvNSSeMdQIwNDY2MTc1NjSycnI2MilQEAs9wyVA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Purine inhibitors of human phosphatidylinositol 3-kinase delta</title><source>esp@cenet</source><creator>Leng, Xiansheng ; Methot, Joey L ; Anthony, Neville John ; Zhou, Hua ; Achab, Abdelghani Abe ; Altman, Michael D ; Ye, Baijun ; Zhao, Xiaoli ; Christopher, Matthew P ; Fradera Llinas, Francesc Xavier ; Mu, Changwei ; Yang, Liping ; Zhang, Sixing ; Deng, Yongqi ; Katz, Jason D ; Garcia, Yudith ; Wang, Xiaona ; Zhang, Rong ; McGowan, Meredeth ; Shi, Feng ; Kattar, Solomon ; Fong, Kin Chiu</creator><creatorcontrib>Leng, Xiansheng ; Methot, Joey L ; Anthony, Neville John ; Zhou, Hua ; Achab, Abdelghani Abe ; Altman, Michael D ; Ye, Baijun ; Zhao, Xiaoli ; Christopher, Matthew P ; Fradera Llinas, Francesc Xavier ; Mu, Changwei ; Yang, Liping ; Zhang, Sixing ; Deng, Yongqi ; Katz, Jason D ; Garcia, Yudith ; Wang, Xiaona ; Zhang, Rong ; McGowan, Meredeth ; Shi, Feng ; Kattar, Solomon ; Fong, Kin Chiu</creatorcontrib><description>The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflamation, asthma, COPD and cancer.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20170615&amp;DB=EPODOC&amp;CC=AU&amp;NR=2013347539B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20170615&amp;DB=EPODOC&amp;CC=AU&amp;NR=2013347539B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Leng, Xiansheng</creatorcontrib><creatorcontrib>Methot, Joey L</creatorcontrib><creatorcontrib>Anthony, Neville John</creatorcontrib><creatorcontrib>Zhou, Hua</creatorcontrib><creatorcontrib>Achab, Abdelghani Abe</creatorcontrib><creatorcontrib>Altman, Michael D</creatorcontrib><creatorcontrib>Ye, Baijun</creatorcontrib><creatorcontrib>Zhao, Xiaoli</creatorcontrib><creatorcontrib>Christopher, Matthew P</creatorcontrib><creatorcontrib>Fradera Llinas, Francesc Xavier</creatorcontrib><creatorcontrib>Mu, Changwei</creatorcontrib><creatorcontrib>Yang, Liping</creatorcontrib><creatorcontrib>Zhang, Sixing</creatorcontrib><creatorcontrib>Deng, Yongqi</creatorcontrib><creatorcontrib>Katz, Jason D</creatorcontrib><creatorcontrib>Garcia, Yudith</creatorcontrib><creatorcontrib>Wang, Xiaona</creatorcontrib><creatorcontrib>Zhang, Rong</creatorcontrib><creatorcontrib>McGowan, Meredeth</creatorcontrib><creatorcontrib>Shi, Feng</creatorcontrib><creatorcontrib>Kattar, Solomon</creatorcontrib><creatorcontrib>Fong, Kin Chiu</creatorcontrib><title>Purine inhibitors of human phosphatidylinositol 3-kinase delta</title><description>The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflamation, asthma, COPD and cancer.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLALKC3KzEtVyMzLyEzKLMkvKlbIT1PIKM1NzFMoyMgvLshILMlMqczJzMsvBkrnKBjrZmfmJRanKqSk5pQk8jCwpiXmFKfyQmluBhU31xBnD93Ugvz41OKCxOTUvNSSeMdQIwNDY2MTc1NjSycnI2MilQEAs9wyVA</recordid><startdate>20170615</startdate><enddate>20170615</enddate><creator>Leng, Xiansheng</creator><creator>Methot, Joey L</creator><creator>Anthony, Neville John</creator><creator>Zhou, Hua</creator><creator>Achab, Abdelghani Abe</creator><creator>Altman, Michael D</creator><creator>Ye, Baijun</creator><creator>Zhao, Xiaoli</creator><creator>Christopher, Matthew P</creator><creator>Fradera Llinas, Francesc Xavier</creator><creator>Mu, Changwei</creator><creator>Yang, Liping</creator><creator>Zhang, Sixing</creator><creator>Deng, Yongqi</creator><creator>Katz, Jason D</creator><creator>Garcia, Yudith</creator><creator>Wang, Xiaona</creator><creator>Zhang, Rong</creator><creator>McGowan, Meredeth</creator><creator>Shi, Feng</creator><creator>Kattar, Solomon</creator><creator>Fong, Kin Chiu</creator><scope>EVB</scope></search><sort><creationdate>20170615</creationdate><title>Purine inhibitors of human phosphatidylinositol 3-kinase delta</title><author>Leng, Xiansheng ; Methot, Joey L ; Anthony, Neville John ; Zhou, Hua ; Achab, Abdelghani Abe ; Altman, Michael D ; Ye, Baijun ; Zhao, Xiaoli ; Christopher, Matthew P ; Fradera Llinas, Francesc Xavier ; Mu, Changwei ; Yang, Liping ; Zhang, Sixing ; Deng, Yongqi ; Katz, Jason D ; Garcia, Yudith ; Wang, Xiaona ; Zhang, Rong ; McGowan, Meredeth ; Shi, Feng ; Kattar, Solomon ; Fong, Kin Chiu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AU2013347539BB23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2017</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>Leng, Xiansheng</creatorcontrib><creatorcontrib>Methot, Joey L</creatorcontrib><creatorcontrib>Anthony, Neville John</creatorcontrib><creatorcontrib>Zhou, Hua</creatorcontrib><creatorcontrib>Achab, Abdelghani Abe</creatorcontrib><creatorcontrib>Altman, Michael D</creatorcontrib><creatorcontrib>Ye, Baijun</creatorcontrib><creatorcontrib>Zhao, Xiaoli</creatorcontrib><creatorcontrib>Christopher, Matthew P</creatorcontrib><creatorcontrib>Fradera Llinas, Francesc Xavier</creatorcontrib><creatorcontrib>Mu, Changwei</creatorcontrib><creatorcontrib>Yang, Liping</creatorcontrib><creatorcontrib>Zhang, Sixing</creatorcontrib><creatorcontrib>Deng, Yongqi</creatorcontrib><creatorcontrib>Katz, Jason D</creatorcontrib><creatorcontrib>Garcia, Yudith</creatorcontrib><creatorcontrib>Wang, Xiaona</creatorcontrib><creatorcontrib>Zhang, Rong</creatorcontrib><creatorcontrib>McGowan, Meredeth</creatorcontrib><creatorcontrib>Shi, Feng</creatorcontrib><creatorcontrib>Kattar, Solomon</creatorcontrib><creatorcontrib>Fong, Kin Chiu</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Leng, Xiansheng</au><au>Methot, Joey L</au><au>Anthony, Neville John</au><au>Zhou, Hua</au><au>Achab, Abdelghani Abe</au><au>Altman, Michael D</au><au>Ye, Baijun</au><au>Zhao, Xiaoli</au><au>Christopher, Matthew P</au><au>Fradera Llinas, Francesc Xavier</au><au>Mu, Changwei</au><au>Yang, Liping</au><au>Zhang, Sixing</au><au>Deng, Yongqi</au><au>Katz, Jason D</au><au>Garcia, Yudith</au><au>Wang, Xiaona</au><au>Zhang, Rong</au><au>McGowan, Meredeth</au><au>Shi, Feng</au><au>Kattar, Solomon</au><au>Fong, Kin Chiu</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Purine inhibitors of human phosphatidylinositol 3-kinase delta</title><date>2017-06-15</date><risdate>2017</risdate><abstract>The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflamation, asthma, COPD and cancer.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_AU2013347539BB2
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Purine inhibitors of human phosphatidylinositol 3-kinase delta
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-24T12%3A21%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Leng,%20Xiansheng&rft.date=2017-06-15&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EAU2013347539BB2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true