Purine inhibitors of human phosphatidylinositol 3-kinase delta

The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflamation, asthma, COPD and cancer.

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Bibliographische Detailangaben
Hauptverfasser:	Leng, Xiansheng, Methot, Joey L, Anthony, Neville John, Zhou, Hua, Achab, Abdelghani Abe, Altman, Michael D, Ye, Baijun, Zhao, Xiaoli, Christopher, Matthew P, Fradera Llinas, Francesc Xavier, Mu, Changwei, Yang, Liping, Zhang, Sixing, Deng, Yongqi, Katz, Jason D, Garcia, Yudith, Wang, Xiaona, Zhang, Rong, McGowan, Meredeth, Shi, Feng, Kattar, Solomon, Fong, Kin Chiu
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflamation, asthma, COPD and cancer.