Platelet-derived growth factor B specific antibodies and compositions and uses thereof

Platelet-derived growth factor B specific antibodies and compositions and uses thereof

The present invention provides antibodies, or antigen-binding fragment thereof, which specifically bind to PDGF-B. The invention further provides a method of obtaining such antibodies and nucleic acids encoding the same. The invention further relates to compositions and therapeutic methods for use o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: RAUCHENBERGER, ROBERT, ARCH, ROBERT, MOSYAK, LYDIA, PONSEL, DIRK, OGAWA, SHINJI, KUAI, JUN, CARVEN, GREGORY
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention provides antibodies, or antigen-binding fragment thereof, which specifically bind to PDGF-B. The invention further provides a method of obtaining such antibodies and nucleic acids encoding the same. The invention further relates to compositions and therapeutic methods for use of these antibodies for the treatment and/or prevention of PDGF-B mediated diseases, disorders or conditions.