Process for preparation of MK-7 type of vitamin K2

Process for preparation of MK-7 type of vitamin K2 is characterized by attaching hexaprenyl chain of all-trans" configuration to monoprenyl derivative of menadiol following 1 + 6" synthetic strategy. According to the invention, a-sulfonyl carbanion generated in situ from the protected mono...

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Bibliographische Detailangaben
Hauptverfasser:	MORZYCKI, JACEK, WINIARSKI, JERZY, KUTNER, ANDRZEJ, KRAJEWSKI, KRZYSZTOF, KUBISZEWSKI, MAREK, WITKOWSKI, STANISLAW, GUTOWSKA, JADWIGA, NAPIORKOWSKI, MAREK, DZIKOWSKA, JADWIGA, BAJ, ANETA, WALEJKO, PIOTR, JEDYNAK, LUKASZ
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY METALLURGY ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:	Process for preparation of MK-7 type of vitamin K2 is characterized by attaching hexaprenyl chain of all-trans" configuration to monoprenyl derivative of menadiol following 1 + 6" synthetic strategy. According to the invention, a-sulfonyl carbanion generated in situ from the protected monoprenyl menadiol of the formula (II), wherein R