Method

The use of Akt3 as a biomarker for detecting the occurrence of epithelial-to- mesenchymal transition (EMT) in a subject, and the use of Akt3 inhibitors to treat cancer is disclosed herein. Also disclosed are various methods for detecting the occurrence of epithelial-to-mesenchymal transition (EMT) i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tiron, Crina, Lorens, Jim
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The use of Akt3 as a biomarker for detecting the occurrence of epithelial-to- mesenchymal transition (EMT) in a subject, and the use of Akt3 inhibitors to treat cancer is disclosed herein. Also disclosed are various methods for detecting the occurrence of epithelial-to-mesenchymal transition (EMT) in a subject by measuring Akt3 expression and/or activity.