Cyclic bridgehead ether DGAT1 inhibitors

The invention relates to compounds of formula (I): (I) useful for treating disorders mediated by acyl coA-diacylglycerol acyl transferase 1 (DGAT1), e.g. metabolic disorders. The invention also provides methods of treating such disorders, and compounds and compositions etc. for their treatment.

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Bibliographische Detailangaben
Hauptverfasser:	MAO, JUSTIN YIK CHING, ZHENG, XUCHUN, CHEN, XIN, ZECRI, FREDERIC, ZHENG, RUI, DUVADIE, ROHIT, PATEL, SEJAL, LIU, QIAN, YE, JIONG, ZHOU, YIZONG, LARROW, JAY, HARRISON, TYLER, DING, YIPING, GAI, YU
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to compounds of formula (I): (I) useful for treating disorders mediated by acyl coA-diacylglycerol acyl transferase 1 (DGAT1), e.g. metabolic disorders. The invention also provides methods of treating such disorders, and compounds and compositions etc. for their treatment.