PROCESS FOR CELL CULTURING BY CONTINUOUS PERFUSION AND ALTERNATING TANGENTIAL FLOW

Use of a process wherein a cell culture comprising cell culture medium and a suspension of cells is circulated over a filter module comprising hollow fibers wherein the flow within the filter module is an alternating tangential flow, for the reduction of the degree of aggregation of the cells in the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	CROWLEY, JOHN, WUBBEN, MAIKE, COCO MARTIN, JOSE MANUEL
Format:	Patent
Sprache:	eng
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Use of a process wherein a cell culture comprising cell culture medium and a suspension of cells is circulated over a filter module comprising hollow fibers wherein the flow within the filter module is an alternating tangential flow, for the reduction of the degree of aggregation of the cells in the cell culture wherein these cells have the tendency to easily or inherently form aggregates during culturing.