Heteroaryl compounds useful as inhibitors of E1 activating enzymes

H:\SXD\lnienvoven\NRPortbl\DCC\SXD\5060770_ .doc-4/9/2013 This invention relates to compounds that inhibit El activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation...

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Bibliographische Detailangaben
Hauptverfasser:	MIZUTANI, HIRO, CULLIS, COURTNEY, WEATHERHEAD, GABRIEL S, VYSKOCIL, STEPAN, VISIERS, IRACHE, OLHAVA, EDWARD J, LANGSTON, STEVEN P, PELUSO, STEPHANE, CLAIBORNE, CHRISTOPHER F, CRITCHLEY, STEPHEN
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	H:\SXD\lnienvoven\NRPortbl\DCC\SXD\5060770_ .doc-4/9/2013 This invention relates to compounds that inhibit El activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders; and inflammation associated with infection and cachexia.