METHOD AND MEDICAMENT FOR INHIBITING THE EXPRESSION OF A DEFINED GENE

An oligoribonucleotide having a double stranded structure (dsRNA), comprising two separate RNA strands, wherein one s strand of the dsRNA has a region I which is complementary to an RNA transcript of at least a part of a target gene, wherein the region is not more than 49 nucleotides in length, and...

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Hauptverfasser: KREUTZER, ROLAND, LIMMER, STEPHAN
Format: Patent
Sprache:eng
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Zusammenfassung:An oligoribonucleotide having a double stranded structure (dsRNA), comprising two separate RNA strands, wherein one s strand of the dsRNA has a region I which is complementary to an RNA transcript of at least a part of a target gene, wherein the region is not more than 49 nucleotides in length, and wherein the target gene is a mammalian gene. 41 15836_1 (GHMatters) P42794.AU.4 27102/13