Compounds and methods for enhancing innate immune responses

Compounds and methods for enhancing innate immune responses

Provided are certain compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections. The present invention relates to compounds that act as enhancers of the host's immune response. The compoun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CATALANO, JOHN GEORGE, CHERN, WENDY HUANG, MOORE, CHRISTOPHER BROOKS, SHOTWELL, JOHN BRADFORD, HAMATAKE, ROBERT, HOFLAND, HANS, THERRIEN, JEAN-PHILIPPE, BANKA, ANNA LINDSEY, YOU, SHIHYUN, TALLANT, MATTHEW DAVID, GARTLAND, MARGARET J, KEICHER, JESSE DANIEL, BOTYANSZKI, JANOS, DICKSON, HAMILTON D, BURROUGHS, ERIC GREGORY
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Provided are certain compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections. The present invention relates to compounds that act as enhancers of the host's immune response. The compounds are believed to up-regulate expression and/or activity of one or more of these proteins, thereby leading to better viral defense and/or treatment.