Acyclic cyanoethylpyrazoles as janus kinase inhibitors

Acyclic cyanoethylpyrazoles as janus kinase inhibitors

The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

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Bibliographische Detailangaben
Hauptverfasser: CLOSE, JOSHUA T, MARTINEZ, MICHELLE, ZHANG, HONGJUN, WHITE, CATHERINE, JUNG, JOON, BRUBAKER, JASON, YOUNG, JONATHAN R, WILSON, KEVIN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.