Cyanomethylpyrazole carboxamides as janus kinase inhibitors

The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

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Bibliographische Detailangaben
Hauptverfasser:	KATZ, JASON DAVID, SIU, TONY, JUNG, JOON, WOO, HYUN CHONG, BRUBAKER, JASON, SILIPHAIVANH, PHIENG, YOUNG, JONATHAN R, CLOSE, JOSHUA T, ZHANG, HONGJUN, CHRISTOPHER, MATTHEW, CHILDERS, MATTHEW LLOYD, TORRES, LUIS E, PETERSON, SCOTT, SMITH, GRAHAM FRANK
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.