Anti-aplhabeta TCR antibody

The present invention relates to humanized monoclonal antibodies comprising the CDRs of murine antibody BMA031, which bind to the apTCR.CD3 complex and possess improved biological properties.

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Bibliographische Detailangaben
Hauptverfasser:	SNELL, DANIEL, QIU, HUAWEI, KEBBLE, BENJAMIN, MENRAD, ANDREAS, PAN, CLARK, LACORCIA, GINA, SHANKARA, SHRINIVAS
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention relates to humanized monoclonal antibodies comprising the CDRs of murine antibody BMA031, which bind to the apTCR.CD3 complex and possess improved biological properties.