Bovine polyclonal antibody specific for human TNF

The disclosure provides a composition comprising polyclonal antibodies that specifically bind to human tumor necrosis factor (hTNF) wherein the polyclonal antibodies are derived from the serum, milk or colostrum of a bovine animal that has been immunized with hTNF or an immunogenic portion thereof....

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Bibliographische Detailangaben
Hauptverfasser: QUESENBERRY, MICHAEL S, FOX, BARBARA S, SCHLEHUBER, LISA D, BOSTWICK, EILEEN F, TRACEY, DANIEL E
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The disclosure provides a composition comprising polyclonal antibodies that specifically bind to human tumor necrosis factor (hTNF) wherein the polyclonal antibodies are derived from the serum, milk or colostrum of a bovine animal that has been immunized with hTNF or an immunogenic portion thereof. Further provided are the methods for antigenic specificity analysis of the anti-hTNF polyclonal antibodies.