Targets and agents for the treatment of impaired bone fracture healing

The application teaches a composition comprising one or more pharmaceutical active ingredients selected from the group consisting of interleukin-8 (IL-8 or CXCL8), a functional fragment of IL-8, a functional variant of IL-8, andan agonist of IL-8 receptor,for therapeutic and/orprophylactic intervent...

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Hauptverfasser: HAUZEUR, JEAN-PHILIPPE, MATHIEU, MYRIELLE, SPRUYT, DELPHINE, PESESSE, XAVIER, DE SENY, DOMINIQUE, GANGJI, VALERIE, INGELS, AUDE, ALBARANI, VALENTINA, RIGUTTO, SABRINA, BASTIANELLI, ENRICO, MAILAISE, MICHEL
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Sprache:eng
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Zusammenfassung:The application teaches a composition comprising one or more pharmaceutical active ingredients selected from the group consisting of interleukin-8 (IL-8 or CXCL8), a functional fragment of IL-8, a functional variant of IL-8, andan agonist of IL-8 receptor,for therapeutic and/orprophylactic interventions in impaired bone fracture healing, such as but not limited to non-union fractures, mal-union fractures,or delayed union fractures.