Bispecific anti-CXCR7 immunoglobulin single variable domains

Bispecific anti-CXCR7 immunoglobulin single variable domains

The present invention relates to particular polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to host cells expressing or capable of expressing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such pol...

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Bibliographische Detailangaben
Hauptverfasser: LEURS, REGORIUS, VAN ROY, MAARTEN, VAN ROMPAEY, PHILIPPE, DESCAMPS, FRANCIS, MERCHIERS, PASCAL GERARD, VANLANDSCHOOT, PETER, GONZALEZ PAJUELO, MARIA, SMIT, MARTINE, STORTELERS, CATELIJNE, MAUSSANG-DETAILLE, DAVID ANDRE BAPTIST
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The present invention relates to particular polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to host cells expressing or capable of expressing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the present invention provides immunoglobulin single variable domains inhibiting CXCR7 mediated tumour growth.