Novel sulfonaminoquinoline hepcidin antagonists
The present invention relates to novel hepcidin antagonists of formula (I), pharmaceutical compositions comprising them and the use thereof as medicaments for the use in the treatment of iron metabolism disorders, such as, in particular, iron deficiency diseases and anaemias, in particular anaemias...
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| creator | BUHR, WILM DAVENPORT, TARA DURRENBERGER, FRANZ CORDEN, VINCENT ANTHONY RIDGILL, MARK PETER DAWSON, GRAHAM FUNK, FELIX SLACK, MARK COURTNEY, STEPHEN MARTIN BURCKHARDT, SUSANNA GEISSER, PETER OTTO BOYCE, SUSAN YARNOLD, CHRISTOPHER JOHN ELLENBROEK, ALBERTUS ANTONIUS |
| description | The present invention relates to novel hepcidin antagonists of formula (I), pharmaceutical compositions comprising them and the use thereof as medicaments for the use in the treatment of iron metabolism disorders, such as, in particular, iron deficiency diseases and anaemias, in particular anaemias in connection with chronic inflammatory diseases (ACD: anaemia of chronic disease and Al; anaemia of inflammation). |
| format | Patent |
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DAVENPORT, TARA ; DURRENBERGER, FRANZ ; CORDEN, VINCENT ANTHONY ; RIDGILL, MARK PETER ; DAWSON, GRAHAM ; FUNK, FELIX ; SLACK, MARK ; COURTNEY, STEPHEN MARTIN ; BURCKHARDT, SUSANNA ; GEISSER, PETER OTTO ; BOYCE, SUSAN ; YARNOLD, CHRISTOPHER JOHN ; ELLENBROEK, ALBERTUS ANTONIUS</creatorcontrib><description>The present invention relates to novel hepcidin antagonists of formula (I), pharmaceutical compositions comprising them and the use thereof as medicaments for the use in the treatment of iron metabolism disorders, such as, in particular, iron deficiency diseases and anaemias, in particular anaemias in connection with chronic inflammatory diseases (ACD: anaemia of chronic disease and Al; anaemia of inflammation).</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130822&DB=EPODOC&CC=AU&NR=2012217021A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130822&DB=EPODOC&CC=AU&NR=2012217021A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BUHR, WILM</creatorcontrib><creatorcontrib>DAVENPORT, TARA</creatorcontrib><creatorcontrib>DURRENBERGER, FRANZ</creatorcontrib><creatorcontrib>CORDEN, VINCENT ANTHONY</creatorcontrib><creatorcontrib>RIDGILL, MARK PETER</creatorcontrib><creatorcontrib>DAWSON, GRAHAM</creatorcontrib><creatorcontrib>FUNK, FELIX</creatorcontrib><creatorcontrib>SLACK, MARK</creatorcontrib><creatorcontrib>COURTNEY, STEPHEN MARTIN</creatorcontrib><creatorcontrib>BURCKHARDT, SUSANNA</creatorcontrib><creatorcontrib>GEISSER, PETER OTTO</creatorcontrib><creatorcontrib>BOYCE, SUSAN</creatorcontrib><creatorcontrib>YARNOLD, CHRISTOPHER JOHN</creatorcontrib><creatorcontrib>ELLENBROEK, ALBERTUS ANTONIUS</creatorcontrib><title>Novel sulfonaminoquinoline hepcidin antagonists</title><description>The present invention relates to novel hepcidin antagonists of formula (I), pharmaceutical compositions comprising them and the use thereof as medicaments for the use in the treatment of iron metabolism disorders, such as, in particular, iron deficiency diseases and anaemias, in particular anaemias in connection with chronic inflammatory diseases (ACD: anaemia of chronic disease and Al; 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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Novel sulfonaminoquinoline hepcidin antagonists |
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