Novel sulfonaminoquinoline hepcidin antagonists

The present invention relates to novel hepcidin antagonists of formula (I), pharmaceutical compositions comprising them and the use thereof as medicaments for the use in the treatment of iron metabolism disorders, such as, in particular, iron deficiency diseases and anaemias, in particular anaemias...

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Bibliographische Detailangaben
Hauptverfasser:	BUHR, WILM, DAVENPORT, TARA, DURRENBERGER, FRANZ, CORDEN, VINCENT ANTHONY, RIDGILL, MARK PETER, DAWSON, GRAHAM, FUNK, FELIX, SLACK, MARK, COURTNEY, STEPHEN MARTIN, BURCKHARDT, SUSANNA, GEISSER, PETER OTTO, BOYCE, SUSAN, YARNOLD, CHRISTOPHER JOHN, ELLENBROEK, ALBERTUS ANTONIUS
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to novel hepcidin antagonists of formula (I), pharmaceutical compositions comprising them and the use thereof as medicaments for the use in the treatment of iron metabolism disorders, such as, in particular, iron deficiency diseases and anaemias, in particular anaemias in connection with chronic inflammatory diseases (ACD: anaemia of chronic disease and Al; anaemia of inflammation).