Piperidine derivatives as NK1 antagonists

OF THE INVENTION A compound having the general structure shown in Formula I: R' R2 Ar2 R4,N )n 5 Ar 0 R (I) or pharmaceutically acceptable salts and/or solvates thereof are useful in treating diseases or conditions mediated by NK1 receptors, for example 10 various physiological disorders, sympt...

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Bibliographische Detailangaben
Hauptverfasser:	TSUI, HONUNG, RAO, ASHWIN U, WROBLESKI, MICHELLE LACI, SHAH, SAPNA S, XIAO, DONG, SHIH, NENG-YANG, HUANG, XIANHAI, PALANI, ANANDAN, WANG, CHENG, PALIWAL, SUNIL
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	OF THE INVENTION A compound having the general structure shown in Formula I: R' R2 Ar2 R4,N )n 5 Ar 0 R (I) or pharmaceutically acceptable salts and/or solvates thereof are useful in treating diseases or conditions mediated by NK1 receptors, for example 10 various physiological disorders, symptoms or diseases, including emesis, depression, anxiety and cough.