CCR9 inhibitors and methods of use thereof

C:\NHPonblI)CC\ R'j I2 _ .gI) OC.21AIv Il2 The invention relates to compounds represented by Structural Formula 1, which can bind to CCR9 receptors and block the binding of a ligand (e.g., TECK) to the receptors. The invention also relates to a method of inhibiting a function of CCR9, and to th...

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Bibliographische Detailangaben
Hauptverfasser: HARRIMAN, GERALDINE C. B, SHI, ZHAN, FLEMING, PAUL, CHEN, SHAOWU
Format: Patent
Sprache:eng
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Zusammenfassung:C:\NHPonblI)CC\ R'j I2 _ .gI) OC.21AIv Il2 The invention relates to compounds represented by Structural Formula 1, which can bind to CCR9 receptors and block the binding of a ligand (e.g., TECK) to the receptors. The invention also relates to a method of inhibiting a function of CCR9, and to the use coiIpounds represented by Structural Formula I in research, therapeutic, prophylactic and diagnostic methods.