Novel heterocyclic compounds and uses thereof

Novel heterocyclic compounds and uses thereof

C.WRV'otbDCkii ta4S9- II)DC.22A)201 2 Al3STRACT New substituted heterocyclic compounds, compositions containing them, and methods of using them for the inhibition of Raf kinase activity are provided. The new compounds and compositions may he used either alone or in combination with at least one...

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Hauptverfasser: SMITH, AARON, XU, YONGJIN, ZHANG, QIONG, JIN, JEFF, MACHAJEWSKI, TIMOTHY D, SENDZIK, MARTIN, ANTONIOS-MCCREA, WILLIAM R, POON, DANIEL, SHAFER, CYNTHIA M, MCKENNE, MAUREEN, RENHOWE, PAUL A, HUANG, ZILIN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:C.WRV'otbDCkii ta4S9- II)DC.22A)201 2 Al3STRACT New substituted heterocyclic compounds, compositions containing them, and methods of using them for the inhibition of Raf kinase activity are provided. The new compounds and compositions may he used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.