Combination of angiopoietin-2 antagonist and of VEGF-A, KDR and/or Flt1 antagonist for treating cancer

"Combination of angiopoietin-2 antagonist and of VEGF-A, KDR and/or FitI antagonist for treating cancer" The invention relates to agents which possess anti-angiogenic activity and are accordingly useful in methods of treatment of disease states associated with angiogenesis in the animal or...

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Bibliographische Detailangaben
Hauptverfasser:	EMERY, STEPHEN CHARLES, BROWN, JEFFREY LESTER, BLAKEY, DAVID CHARLES
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	"Combination of angiopoietin-2 antagonist and of VEGF-A, KDR and/or FitI antagonist for treating cancer" The invention relates to agents which possess anti-angiogenic activity and are accordingly useful in methods of treatment of disease states associated with angiogenesis in the animal or human body. More specifically the invention concerns a combination of an antagonist of the biological activity of Angiopoietin-2 and an antagonist of the biological activity of VEGF-A, and/or KDR, and/or Fltl, and uses of such antagonists. C:\NRPonbl\DCC\REC\4258509_1.DOC - 11/4/12