Substituted tetracycline compounds

The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline 5 compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compou...

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Hauptverfasser: ASSEFA, HAREGEWEIN, BOWSER, TODD, BERNIAC, JOEL, NIHLAWI, MOHAMMED, MECHICHE, RACHID, OHEMENG, KWASI, KIM, OAK, BHATIA, BEENA, ABATO, PAUL, HONEYMAN, LAURA, GRIER, MARK, HOHOS, AARON, CHEN, JACKSON, SIZENSKY, EMMANUELLE, AMOO, VICTOR, NELSON, MARK L, MAIL, MOHAMED Y
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline 5 compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.