Sulfonylpiperazine derivatives that interact with glucokinase regulatory protein for the treatment of diabetes

Sulfonylpiperazine derivatives that interact with glucokinase regulatory protein for the treatment of diabetes

The present invention relates to compounds of Formula I, or pharmaceutically acceptable salts thereof, that interact with glucokinase regulatory protein. In addition, the present invention relates to methods of treating type 2 diabetes, and other diseases and/or conditions where glucokinase regulato...

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Hauptverfasser: KUNZ, ROXANNE KAY, TEGLEY, CHRISTOPHER MICHAEL, ASHTON, KATE, BO, YUNXIN, NISHIMURA, NOBUKO, PENNINGTON, LEWIS DALE, BARTBERGER, MICHAEL DAVID, FOTSCH, CHRISTOPHER HAROLD, HALE, CLARENCE HENDERSON, TAMAYO, NURIA A, BRYAN, MARIAN C, NORMAN, MARK H, YANG, KEVIN CHAO, CROGHAN, MICHAEL, POON, STEVE FONG, STEC, MARKIAN MYROSLAW, ST. JEAN JR., DAVID JOSEPH, LIU, LONGBIN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention relates to compounds of Formula I, or pharmaceutically acceptable salts thereof, that interact with glucokinase regulatory protein. In addition, the present invention relates to methods of treating type 2 diabetes, and other diseases and/or conditions where glucokinase regulatory protein is involved using the compounds, or pharmaceutically acceptable salts thereof, and pharmaceutical compositions that contain the compounds, or pharmaceutically acceptable salts thereof.