Novel formulation of pegylated-liposome encapsulated glycopeptide antibiotics

This invention is directed to a novel method of treating an individual suffering from a bacterial infection, such as bacterial infections of various tissues or organs of an individual. In general, the method of treatment involves administering to an individual a pharmaceutical formulation that compr...

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Bibliographische Detailangaben
Hauptverfasser: PUMERANTZ, ANDREW, WANG, JINGHUA JEFFREY, BETAGERI, GURU
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention is directed to a novel method of treating an individual suffering from a bacterial infection, such as bacterial infections of various tissues or organs of an individual. In general, the method of treatment involves administering to an individual a pharmaceutical formulation that comprises a liposome-encapsulated antimicrobial agent, wherein polyethylene glycol (PEG) molecules are covalently attached to the surface of the liposomes.