Novel amide derivative and use thereof as medicine

Provided is a novel low molecular weight compound which inhibits the production of inducible MMPs, in particular MMP-9, rather than the production of constitutive MMP-2. Also provided is a prophylactic and/or therapeutic agent for an autoimmune disease or arthrosis deformans. An amide derivative rep...

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Bibliographische Detailangaben
Hauptverfasser:	Maeda, Kazuhiro, Ishibuchi, Seigo, Tashiro, Kaoru, Tarao, Akiko, Endoh, Jun-ichi, Hikawa, Hidemasa
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided is a novel low molecular weight compound which inhibits the production of inducible MMPs, in particular MMP-9, rather than the production of constitutive MMP-2. Also provided is a prophylactic and/or therapeutic agent for an autoimmune disease or arthrosis deformans. An amide derivative represented by formula (I) [wherein each symbol is as defined in the specification], or a pharmacologically acceptable salt thereof.