Inhibitors of protein tyrosine kinase activity and use thereof to treat ophthalmic disorders

Inhibitors of protein tyrosine kinase activity and use thereof to treat ophthalmic disorders

Disclosed are compounds, and compositions of same, that are protein tyrosine kinase inhibitors. The compounds find use in the treatment of ophthalmic diseases, disorders and conditions. Said compounds are of the formulae (I), (II) or (III). Wherein R = (IV), (V), (VI), (VII), (VIII), (IX), (X), (XI)...

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Bibliographische Detailangaben
Hauptverfasser: GAUDETTE, FREDERIC, CLARIDGE, STEPHEN WILLIAM, RAEPPEL, STEPHANE, ZHAN, LIJIE, RAEPPEL, FRANCK, VAISBURG, ARKADII
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Disclosed are compounds, and compositions of same, that are protein tyrosine kinase inhibitors. The compounds find use in the treatment of ophthalmic diseases, disorders and conditions. Said compounds are of the formulae (I), (II) or (III). Wherein R = (IV), (V), (VI), (VII), (VIII), (IX), (X), (XI) or (XII).