Method and apparatus for in vitro testing for medical devices

Apparatus for simulating a female vagina includes a pressure chamber, a vaginal model disposed in a pressure chamber and means to deliver liquid into the vaginal model. The pressure chamber includes an interior, first means to provide fluid pressure to the pressure chamber, and second means to provide localized fluid pressure within the pressure chamber. The vaginal model includes a wall that (1 ) defines a vaginal lumen extending inwardly from a vaginal opening associated with a bore through an exterior surface of the pressure chamber to vaginal fornices adjacent a cervical port; (2) has an outer surface comprising an anterior vaginal surface and a posterior vaginal surface; and (3) has at least one passage for providing a fluid to the cervical port. Methods for using this apparatus are also disclosed.