Anaplastic lymphoma kinase modulators and methods of use

Abstract The present invention comprises compounds and pharmaceutical compositions comprising the compounds that are inhibitors of ALK. The invention also comprises methods of using the compounds and compositions to treat diseases mediated by ALK, including diseases such as cancer, immunological dis...

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Bibliographische Detailangaben
Hauptverfasser:	MANALO, JEAN-CLAIRE L, BUSSENIUS, JOERG, KENNEDY, ABIGAIL R, PETO, CSABA J, DUBENKO, LARISA, KHOURY, RICHARD G, CURTIS, JEFFRY KIMO, BLAZEY, CHARLES M, COSTANZO, SIMONA, KIM, ANGIE I, BOWLES, OWEN JOSEPH, ANAND, NEEL KUMAR, RICE, KENNETH D, TSANG, TSZE H
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Abstract The present invention comprises compounds and pharmaceutical compositions comprising the compounds that are inhibitors of ALK. The invention also comprises methods of using the compounds and compositions to treat diseases mediated by ALK, including diseases such as cancer, immunological disorders, cardiovascular diseases, and other degenerative disorders.